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N-acyldihydropyridones as synthetic intermediates. synthesis of (±)-septicine and (±)-tylophorine.

✍ Scribed by Daniel L. Comins; Lawrence A. Morgan

Publisher: Elsevier Science
Year: 1991
Tongue: French
Weight: 247 KB
Volume: 32
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)79426-3

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✦ Synopsis

The mdohzrdme alkalords (+)-septlane and (k)-tylophonne were prepared from N-acyldLhydropyndone 7 tn five and SW steps, respectively

Recently we hdve been studying the synthesis and synthetic utility of N-acyl-2,3-dlhydm-4-pyndoneq These highly functlonJlzed heterocycles are conveniently prepared by the addition of Gngnard reagents to 1-acyl-4-methoxypyndlnlun~ s&s ' Previously, plpendme2, qumol~zldme'~3, and crs-decahydroqulnohne4

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