N-acyl-1,4-dihydropyridines by acid catalyzed condensations

✍ Scribed by Joseph S. Foos; William Killian; S.Q.A. Rizvi; Michael Unger; Gideon Fraenkel

• Book ID: 104245611
• Publisher: Elsevier Science
• Year: 1978
• Tongue: French
• Weight: 141 KB
• Volume: 19
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)94558-7

✦ Synopsis

Dihydropyridines have been prepared via the Hantzsch synthesis', by reduction of pyridines2 and condensation reactions usingglutara1dehydes.s These procedures are often plagued by low yields and unwanted side-products.

We have used N-acyl-1,4_dihydropyridines 1 as precursors of dihydropyridine anions, 5,