𝔖 Bobbio Scriptorium
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N-Acetylneuraminic Acid: a Constituent of the Lipopolysaccharide of Salmonella toucra

✍ Scribed by Barbara KȨDZIERSKA


Book ID
115116949
Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
688 KB
Volume
91
Category
Article
ISSN
1432-1327

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A new synthesis of N-acetylneuraminic ac
✍ René Csuk; Martin Hugener; Andrea Vasella 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 German ⚖ 649 KB

A new synthesis of N-acetylneuraminic acid (NeuSAc; 28) via the aldehyde 10 is described. The aldehyde 10 was obtained from N-acetyl-o-glucosamine (11; 5 steps, overall yield ca. 6 %) or from o-glucono-1,s-lactone (17; 6 steps, overall yield ra. 57%). Thus, on the one hand, N-acetyl-D-mannosamine (1