N-Acetyl peak in MR spectra of intracranial metastatic mucinous adenocarcinomas

✍ Scribed by Xiang Liu; Barbara I. Germin; Jianhui Zhong; Sven Ekholm

• Book ID: 103838966
• Publisher: Elsevier Science
• Year: 2010
• Tongue: English
• Weight: 863 KB
• Volume: 28
• Category: Article
• ISSN: 0730-725X
• DOI: 10.1016/j.mri.2010.06.015

✦ Synopsis

Absence of N-acetylaspartate (NAA) is one important diagnostic criterion of MR spectroscopy (MRS) that may suggest that an intracranial mass lesion is a metastasis. We report two cases of histopathology-confirmed intracranial metastatic mucinous adenocarcinoma, which predominantly showed a large metabolite peak at 2.0 ppm, mimicking an NAA peak of normal brain tissue. This finding could be of help in the interpretation of MRS in cases of intracranial enhancing mass lesions, metastases or gliomas.