N -(3,3a,4,4a,5,5a,6,6a-Octahydro-1,3-dioxo-4,6- ethenocycloprop[f]isoindol-2-(1 H )-yl)carboxamides: Identification of Novel Orthopoxvirus Egress Inhibitors
✍ Scribed by Bailey, Thomas R.; Rippin, Susan R.; Opsitnick, Elizabeth; Burns, Christopher J.; Pevear, Daniel C.; Collett, Marc S.; Rhodes, Gerry; Tohan, Sanjeev; Huggins, John W.; Baker, Robert O.; Kern, Earl R.; Keith, Kathy A.; Dai, Dongcheng; Yang, Guang; Hruby, Dennis; Jordan, Robert
- Book ID
- 118012268
- Publisher
- American Chemical Society
- Year
- 2007
- Tongue
- English
- Weight
- 94 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0022-2623
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📜 SIMILAR VOLUMES
In the molecule of the title compound, C 23 H 20 ClFN 2 O 4 , the cyclohexene ring is not planar and has a flattened boat conformation. Intermolecular C-HÁ Á ÁO hydrogen bonds, linking the independent molecules into dimers, may be effective in the stabilization of the crystal structure.
## Abstract A series of 3a,5‐diaryl‐1,3‐diphenyl‐3a,4,5,6‐tetrahydro‐3H‐1,2,4‐triazolo[4,3‐a][1,5]benzo‐diazepines was synthesized by the cycloaddition reactions of 2,4‐diaryl‐2,3‐dihydro‐1H‐1,5‐benzo‐diazepines and N‐phenylbenzonitrileimine generated from N‐phenylbenzenecarbohydrazonic chloride in
The title compound, C 21 H 20 ClN 3 O 2 , was synthesized by the reaction of 4-chlorobenzaldehyde and 3-(5,5-dimethyl-3-oxocyclohex-1-enylamino)propanoic acid with malononitrile in ethylene glycol under microwave irradiation. The dihydropyridine ring has a boat conformation. The pyrimidine ring adop