Synthesis of (5R,6S)-6-[(1R)-hydroxyethy
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J. E. Swigor; C. U. Kim; K. A. Pittman
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Article
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1988
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John Wiley and Sons
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French
โ 198 KB
The synthesis of the title compound (4) is described. ## Treatment of (3S)-[(lR)-hydroxyethyl]-(4R)- [ 3-(p-nitrobenzyloxy) carbonyl-2-0x0-[ 2-I4C] -3-diazopropan-l-yl]azetidin-2-one1 with rhodium diacetate achieved ring closure forming (5R,6S)-pnitrobenzyl-6-~(1R)-hydroxyethyl]-3,7-dioxo-[3-14C]