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Myotonic Dystrophy: The Role of RNA CUG Triplet Repeats

✍ Scribed by Lubov T. Timchenko

Book ID
117852731
Publisher
American Society of Human Genetics
Year
1999
Tongue
English
Weight
198 KB
Volume
64
Category
Article
ISSN
0002-9297

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## Abstract Mental retardation is a main feature of the congenital form of myotonic dystrophy (DM1), however, the molecular mechanisms underlying the central nervous system symptoms of DM1 are poorly understood. We have established a PC12 cell line‐based model expressing the DM1 expanded CUG repeat