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Myostatin induces autophagy in skeletal muscle in vitro

✍ Scribed by Jen Y. Lee; Nicholas S. Hopkinson; Paul R. Kemp

Book ID: 116302566
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 524 KB
Volume: 415
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2011.10.124

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## Abstract Myostatin is a negative regulator of muscle mass and has been reported to be upregulated in several conditions characterized by muscle atrophy. The influence of sepsis on myostatin expression and activity is poorly understood. Here, we tested the hypothesis that sepsis upregulates the e