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Myostatin: a modulator of skeletal-muscle stem cells

✍ Scribed by Walsh, F.S.; Celeste, A.J.

Book ID
121798918
Publisher
Portland Press
Year
2005
Tongue
English
Weight
81 KB
Volume
33
Category
Article
ISSN
0300-5127

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## Abstract By using a conditional gene targeting approach exploiting the cre‐lox system, we show that postnatal inactivation of the myostatin gene in striated muscle is sufficient to cause a generalized muscular hypertrophy of the same magnitude as that observed for constitutive myostatin knockout