𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Myosin autoantibodies reacting with selective muscle fiber types

✍ Scribed by Brian L. McDonald; Dr. Roger L. Dawkins; Jennifer Robinson

Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
638 KB
Volume
2
Category
Article
ISSN
0148-639X

No coin nor oath required. For personal study only.

✦ Synopsis

Myosin in striated muscle exists in at least two immunologically distinct forms. Human autoantibodies specific for either form show selective muscle fiber reactivity. One group of antibodies reacts with type 2b (white) muscle fibers, the other with type 2a (red) and type 1 (intermediate) fibers. All of these antibodies react with the A band of glycerinated myofibrils. Both groups of antibodies react with cardiac muscle. Muscle-fiber-specific antibodies are detected in approximately 1% of sera submitted for diagnostic screening. Sera from eight patients were studied further. The two patients with antibodies against type 2b (white) muscle myosin had rheumatoid arthritis. The six patients with antibodies against type 2a (red) and type 1 (intermediate) myosin had clinical features which included various autoimmune and infectious disorders.

πŸ“œ SIMILAR VOLUMES

Myosin isoforms, muscle fiber types, and
Myosin isoforms, muscle fiber types, and transitions
✍ Dirk Pette; Robert S. Staron πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 127 KB

Skeletal muscle is an extremely heterogeneous tissue composed of a variety of fast and slow fiber types and subtypes. Moreover, muscle fibers are versatile entities capable of adjusting their phenotypic properties in response to altered functional demands. Major differences between muscle fiber type

Fiber types and myosin heavy chain compo
Fiber types and myosin heavy chain composition in muscles of common shrew (Sorex araneus)
✍ Savolainen, Jukka ;Vornanen, Matti πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 1009 KB

Red-toothed shrews of subfamily Soricinae are small mammals with very high mass-specific metabolic rate. Owing to their high aerobic power they are interesting objects for studies concerning the limits and constraints of skeletal muscle adaptation. In order to clarify the correlation between metabol