✦ LIBER ✦
Myopathy with ragged red fibres following renal transplantation: possible role of cyclosporin-induced hypomagnesaemia
✍ Scribed by Andrew J. Larner; Stephen G. Sturman; J. B. Hawkins; Milne Anderson
- Publisher
- Springer-Verlag
- Year
- 1994
- Tongue
- English
- Weight
- 857 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0001-6322
No coin nor oath required. For personal study only.
✦ Synopsis
A 65-year-old man developed a painless proximal myopathy 7 years after commencing cyclosporin therapy following a successful cadaveric renal transplant. Muscle histology showed ragged red fibres and biochemical studies suggested mitochondrial dysfunction. The possible pathogenesis of this mitochondrial myopathy, particularly its relationship to cyclosporin-induced hypomagnesaemia, is discussed.