✦ LIBER ✦

Myokymia, neuromyotonia, dermatomyositis, and voltage-gated K+ channel antibodies

✍ Scribed by Shin J. Oh; Anjaneyulu Alapati; Gwen C. Claussen; Steven Vernino

Publisher: John Wiley and Sons
Year: 2003
Tongue: English
Weight: 108 KB
Volume: 27
Category: Article
ISSN: 0148-639X
DOI: 10.1002/mus.10369

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✦ Synopsis

Abstract

A young woman presented with facial myokymia in association with dermatomyositis. There was no evidence of peripheral neuropathy. Needle electromyography showed prominent myokymic discharges and brief neuromyotonic discharges in addition to many small‐amplitude, short‐duration motor unit potentials. Myokymia and dermatomyositis both responded to immunosuppressive treatment. The presence of antibodies to voltage‐gated potassium channels and the association with dermatomyositis indicated an autoimmune cause for myokymia, which may have been due to reversible peripheral nerve hyperexcitability. Muscle Nerve 27: 757–760, 2003

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