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Myoglobin gene expression attenuates hepatic ischemia reperfusion injury

โœ Scribed by Takashi Nitta; Xu Xundi; Etsuro Hatano; Naritaka Yamamoto; Tetsuya Uehara; Masanori Yoshida; Nobuko Harada; Kazuo Honda; Akira Tanaka; Donna Sosnowski; Britton Chance; Yoshio Yamaoka


Book ID
117169287
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
840 KB
Volume
110
Category
Article
ISSN
0022-4804

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The purpose of this study was to investigate the effectiveness of superoxide dismutase (SOD) overexpression in an acute model of hepatic oxidative stress. Oxidative stress was established using a warm ischemia-reperfusion model, where nearly 70% of the liver was made hypoxic by clamping the hepatic