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Myoepithelial Cells in the Control of Mammary Development and Tumorigenesis: Data From Genetically Modified Mice

✍ Scribed by Marisa M. Faraldo; Jérôme Teulière; Marie-Ange Deugnier; Ilaria Taddei-De La Hosseraye; Jean Paul Thiery; Marina A. Glukhova

Publisher
Springer US
Year
2005
Tongue
English
Weight
313 KB
Volume
10
Category
Article
ISSN
1083-3021

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It has previously been shown that transgenic female mice expressing TGF␤1 under control of regulatory elements of the whey-acidic protein (WAP) gene were unable to lactate. This was due to the increased apoptosis of the cells committed to the lobular-lactogenic phenotype. Our goal was to determine w