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Myocyte enhancer factor-2 transcription factors in neuronal differentiation and survival

✍ Scribed by Kim A. Heidenreich; Daniel A. Linseman

Book ID
111640709
Publisher
Springer
Year
2004
Tongue
English
Weight
389 KB
Volume
29
Category
Article
ISSN
0893-7648

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## Abstract Survival signals such as insulin‐like growth factor‐1 (IGF‐1) or membrane depolarization convey their neuronal protective effects through the activation of signaling networks and nuclear factors. In cerebellar granule neurons, IGF‐1 mediates survival primarily through the PI3K/Akt pathw