## Abstract We investigated whether myoclonus in corticobasal degeneration (CBD) is cortical or subcortical in origin. Many authors have suggested that the myoclonus in CBD is a subtype of cortical myoclonus, despite the fact that backโaveraging fails to detect a cortical correlate to spontaneous o
Myoclonus in corticobasal degeneration
โ Scribed by Dr. Francesco Carella; Claudia Ciano; Ferruccio Panzica; Vidmer Scaioli
- Book ID
- 102948650
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 503 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0885-3185
No coin nor oath required. For personal study only.
โฆ Synopsis
Abstract
Five patients with unilateral myoclonus and a clinical diagnosis of corticobasal degeneration (CBD) were studied. All patients showed enhanced longโloop responses in their myoclonic arms without enlarged somatosensory potentials. The cortical relay time of the longโloop responses was studied in three patients, in two of whom it was <2 ms, even in the nonmyoclonic arm. Myoclonus in CBD is probably related to an enhanced longโloop reflex whose pathway is unlikely to be the same as that in classic cortical reflex myoclonus.
๐ SIMILAR VOLUMES
## Abstract ## OBJECTIVE: To characterize the clinical features, particularly dystonia, in patients with clinically diagnosed or pathologically proven corticobasal degeneration (CBD). ## BACKGROUND: Although dystonia has been reported in many neurodegenerative disorders, it has not been studied