Myoclonus in Alzheimer's disease
โ Scribed by Y. Ugawa; N. Kohara; H. Hirasawa; S. Kuzuhara; M. Iwata; T. Mannen
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 468 KB
- Volume
- 235
- Category
- Article
- ISSN
- 0340-5354
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Increasing attention has been paid to the prominence of myoclonus in Alzheimer's disease of early onset. This was particularly striking in many family members affected by autosomal dominant Alzheimer's disease linked to chromosome 14, as recently reported by Haltia and colleagues { 11 and by Lampe a
Two brothers with clinically definite adult Huntington's disease developed disabling myoclonus years after the first signs of the disease. Their electroencephalograms were consistent with a primary generalized epilepsy, although neither man had seizures. The myoclonus was controlled with valproic ac
## Abstract We describe three patients with Huntington's disease, from two families, in whom myoclonus was the predominant clinical feature. The diagnosis was confirmed at autopsy in two cases and by DNA analysis in all three. These patients all presented before the age of 30 years and were the off