✦ LIBER ✦
Myocardial high energy phosphate metabolism in closed chest dog: Creation of an animal model
✍ Scribed by Dr. Mary Osbakken; Laszlo Ligeti; B. J. Clark; Lizann Bolinger; Hari Subramanian; Mitchell Schnall; Jack Leigh; Britton Chance
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 402 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0740-3194
No coin nor oath required. For personal study only.
✦ Synopsis
A chronic closed chest dog model was developed to study myocardial metabolism with NMR spectroscopy. Cardiac windows were surgically created in 10 dogs by removal of two ribs and accompanying skeletal muscle. Marlex mesh was sewn between the two exposed ribs, and fascia and skin were closed. 3 1 P spectra were obtained using a surface coil placed into the surgically created pouch and using routine NMR pulsing techniques.