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Myocardial guanylate cyclase: Properties of the enzyme and effects of cholinergic agonists in vitro

✍ Scribed by Lee E. Limbird; Robert J. Lefkowitz


Book ID
115734040
Publisher
Elsevier Science
Year
1975
Weight
685 KB
Volume
377
Category
Article
ISSN
0005-2744

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Direct effect of glibenclamide on guanyl
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Glibenclamide enhanced the activity in the rat of guanylate cyclase in a number of extra-pancreatic tissues. Thus, glibenclamide enhanced guanylate cyclase activity in vitro two- to threefold in liver, kidney, heart, spleen and colon at a concentration of 1 mumol/l. Dose-response curves of glibencla