Myo-inositol transport through the blood-brain barrier
β Scribed by Reynold Spector
- Publisher
- Springer
- Year
- 1988
- Tongue
- English
- Weight
- 278 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0364-3190
No coin nor oath required. For personal study only.
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An understanding of the mechanisms of transport of circulating nutrients and hormones through the brain capillary wall, i. e., the blood-brain barrier, is important because the availability in brain of these substances influences a number of cerebral metabolic pathways. For example, the utilization
Efflux transport at the blood-brain barrier (BBB) limits the brain tissue exposure to a variety of potential therapeutic agents, including compounds that are relatively lipophilic and would be predicted to permeate the endothelial lining of the brain microvasculature. Recent advances in molecular an