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Myeloproliferative disorder therapy: assessment and management of adverse events—a dermatologist's perspective

✍ Scribed by Boutros Soutou; Sélim Aractingi


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
106 KB
Volume
27
Category
Article
ISSN
0278-0232

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✦ Synopsis


Abstract

Development of cutaneous manifestations in patients with myeloproliferative disorders can be either due to the course of the disease itself or induced by some of the treatments given. The cutaneous manifestations may reveal an unknown haemopathy and/or indicate a poor prognosis. Some of these alter quality of life. Hydroxyurea has been shown to induce a variety of cutaneous adverse reactions ranging from benign effects such as hyperpigmentation to more severe leg ulcers and squamous cell carcinomas. Herein, we discuss the importance of undertaking regular physical examinations in order to identify and treat cutaneous manifestations early in their course. Copyright © 2009 John Wiley & Sons, Ltd.


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