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Myeloid/natural killer cell precursor blast crisis of chronic myelogenous leukemia with two Philadelphia (Ph-1) chromosomes

✍ Scribed by C. Kahl; A.-F. Pelz; R. Bartsch; K. Jentsch-Ullrich; R. Brückner; H.-P. Fostitsch; A. Franke


Publisher
Springer
Year
2001
Tongue
English
Weight
156 KB
Volume
80
Category
Article
ISSN
0939-5555

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A 23-year-old man developed Ph'-positive chronic myelogenous leukemia in 1966. After two short courses of busulfan not associated with severe myelosuppression, the frequency of Ph'-positive metaphases in his bone marrow was 40%. Over the next eight years, he remained hematologically stable without f