Myeloid-derived suppressor cells in inflammation: Uncovering cell subsets with enhanced immunosuppressive functions
โ Scribed by Vincenzo Bronte
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 94 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Chronic inflammation is associated with promotion of malignancy and tumor progression. Many tumors enhance the accumulation of myeloidโderived suppressor cells (MDSC), which contribute to tumor progression and growth by suppressing antiโtumor immune responses. Tumorโderived ILโ1ฮฒ secret
## Abstract Cannabinoid receptor activation by agents such as ฮ^9^โtetrahydrocannabinol (THC) is known to trigger immune suppression. Here, we show that administration of THC in mice leads to rapid and massive expansion of CD11b^+^Grโ1^+^ myeloidโderived suppressor cells (MDSC) expressing functiona