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Myelodysplastic syndrome with a t(2;11)(p21;q23-24) and translocation breakpoint close to miR-125b-1

✍ Scribed by Jim Thorsen; Hege Vangstein Aamot; Roberta Roberto; Geir E. Tjønnfjord; Francesca Micci; Sverre Heim


Book ID
119211544
Publisher
Elsevier
Year
2012
Tongue
English
Weight
393 KB
Volume
205
Category
Article
ISSN
2210-7762

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Translocation t(11;21)(q24;q11.2) is a rare but recurrent chromosomal abnormality associated with myelodysplastic syndrome (MDS) that until now has not been characterized at the molecular level. We report here results of a molecular cytogenetic analysis of this translocation in a patient with refrac