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Myelin proteolipid protein: An effective autoantigen and target of autoimmunity in multiple sclerosis

✍ Scribed by Judith M. Greer; Michael P. Pender

Book ID: 116614154
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 256 KB
Volume: 31
Category: Article
ISSN: 0896-8411
DOI: 10.1016/j.jaut.2008.04.018

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## Autoreactive T and B cells responding to myelin proteolipid protein in multiple sclerosis and controls* The pathogenesis of multiple sclerosis (MS) could involve an autoimmune response to proteolipid protein (PLP). Immunization of experimental animals with this major myelin protein can lead to