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Myelin basic protein epitopes secreted by human T cells encounter natural autoantibodies in the serum

โœ Scribed by Chiara Guerriero; Gianni Zoccatelli; Elisabetta Stefani; Silvia Sartoris; Tiziana Cestari; Anna Pia Riviera; Giuseppe Tridente; Giancarlo Andrighetto; Roberto Chignola


Book ID
114137993
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
180 KB
Volume
141
Category
Article
ISSN
0165-5728

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Studies from our laboratory have shown that region 69-84 (synthetic peptide S49S) of myelin basic protein (MBP) defines an encephalitogenic sequence for experimental allergic encephalomyelitis (EAE) in Lewis rats. The most potent EAE inducers are the guinea pig MBP (Gp-MBP) and region 69-84, known a