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Mycoplasma hyorhinis upregulates calpastatin and inhibits calpain-dependent proteolysis in SH-SY5Y neuroblastoma cells

✍ Scribed by Esther Elkind; Hagai Rechnitzer; Tali Vaisid; Jonathan D. Kornspan; Sivia Barnoy; Shlomo Rottem; Nechama S. Kosower


Book ID
109331871
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
259 KB
Volume
304
Category
Article
ISSN
0378-1097

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Calpains and calpastatin in SH-SY5Y neur
✍ F. Grynspan; W.B. Griffin; P.S. Mohan; T.B. Shea; R.A. Nixon πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 179 KB πŸ‘ 1 views

Calpains have importance in human neurodegenerative disease pathogenesis, but these mechanisms are difficult to study in postmortem tissues. To establish a cellular model of the human calpain and calpastatin system, we characterized calpain I, calpain II, and calpastatin in SH-SY5Y human neuroblasto