Myc translocations in B cell and plasma cell neoplasms
โ Scribed by Siegfried Janz
- Book ID
- 116410588
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 601 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1568-7864
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## Abstract Recent studies have suggested that chromosomal aberrations of the MYC gene locus indicate an unfavorable prognosis in diffuse large Bโcell lymphoma (DLBCL). However, there have been few reports on MYC translocation in Chinese patients. One hundred and six cases of DLBCLs were analyzed u
Reciprocal translocation between the MYCcarrying chromosome and one of the three Ig loci is a regular feature of certain B-cell-derived tumors in three species: Burkitt's lymphomas (BL) in humans, induced plasmacytomas in Balb/c mice (MPC), and the spontaneous immunocytomas (RIC) of the Louvain rat
## Abstract Plasma cell leukemia (PCL) is a rare form of monoclonal gammopathy, which can originate de novo or evolve from multiple myeloma (MM) as a terminal leukemic phase. Previous cytogenetic studies of PCL have reported the presence of complex karyotypes with involvement of multiple unidentifi