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Myc down-regulation induces apoptosis in M14 melanoma cells by increasing p27kip1 levels

✍ Scribed by D'Agnano, Igea; Valentini, Alessandra; Fornari, Cristina; Bucci, Barbara; Starace, Giuseppe; Felsani, Armando; Citro, Gennaro


Book ID
110064677
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
324 KB
Volume
20
Category
Article
ISSN
0950-9232

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## Abstract Sodium ascorbate (vitamin C) has a reputation for inconsistent effects upon malignant tumor cells, which vary from growth stimulation to apoptosis induction. Melanoma cells were found to be more susceptible to vitamin C toxicity than any other tumor cells. The present study has shown th