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Myasthenia gravis sera have no effect on cardiomyocytes in vitro

✍ Scribed by Geir Helgeland; Steven P. Luckman; Fredrik R. Romi; Anne K. Jonassen; Nils Erik Gilhus


Book ID
113730317
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
757 KB
Volume
201-202
Category
Article
ISSN
0165-5728

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## Abstract Patients with myasthenia gravis can have antibodies against skeletal muscle ryanodine receptor (Ry1), the sarcoplasmic reticulum calcium‐release channel, which plays a crucial role in excitation–contraction coupling. We have screened a panel of overlapping Ry1 fusion proteins with Ry1 a