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Myasthenia gravis and Charcot-Marie-Tooth disease type 1A: An unusual combination of diseases

✍ Scribed by Chiung-Mei Chen; Hong-Shiu Chang; Rong-Kuo Lyu; Lok-Ming Tang; Sien-Tsong Chen

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 31 KB
Volume: 20
Category: Article
ISSN: 0148-639X
DOI: 10.1002/(sici)1097-4598(199711)20:11<1457::aid-mus16>3.0.co;2-z

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✦ Synopsis

Concurrence of myasthenia gravis (MG) and Charcot-Marie-Tooth type 1 (CMT1A) neuropathy is rare. We describe a 60-year-old woman with MG and genetically proved CMT1A. The fluctuating ocular symptoms and proximal limb weakness were markedly improved by pyridostigmine treatment. Recognition of the possible association of MG and CMT1A in the same patient is important because the therapeutic result is rewarding.

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