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Mutations of Tyr447 in protocatechuate 3,4-dioxygenase: Role of the displaceable iron ligand

โœ Scribed by R.W. Frazee; H. Yu; K.B. Dolbeare; J.D. Lipscomb


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
75 KB
Volume
59
Category
Article
ISSN
0162-0134

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Protocatechurate 3,4-dioxygenase (3,4-PCD) has been found in soil bacteria and is known to play a role in degrading aromatic molecules in nature. [1, 2] The enzyme is classified as an intradiol dioxygenase and cleaves catechol analogues bound to the iron(iii) site into aliphatic products with incorp