## Abstract Checkpoint genes, activated in response to DNA damage and other stresses, are frequently targeted for alteration in cancer. Checkpoint kinase 2 (__CHK2, CDS1, RAD53__) is activated by ataxia telangiectasia mutated (ATM) in response to γ irradiation. Activated __CHK2__ stabilizes TP53, a
Mutations of the β - and γ -catenin genes are uncommon in human lung, breast, kidney, cervical and ovarian carcinomas
✍ Scribed by Ueda, M; Gemmill, R M; West, J; Winn, R; Sugita, M; Tanaka, N; Ueki, M; Drabkin, H A
- Book ID
- 111724549
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 98 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0007-0920
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