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Mutations of the p53 tumour suppressor gene in haematologic neoplasms

✍ Scribed by Naoki Mori; Makio Wada; Jun Yokota; Masaaki Terada; Michiko Okada; Masanao Teramura; Michihiko Masuda; Shigeru Hoshino; Toshiko Motoji; Kazuo Oshimi; Hideaki Mizoguchi

Book ID
114713002
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
811 KB
Volume
81
Category
Article
ISSN
0007-1048

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## Abstract A variety of neoplasms of the human nervous system were analyzed for the presence of mutations in the __p53__ tumor suppressor gene. DNA was extracted from frozen or formalin‐fixed, paraffin‐embedded material. Single‐strand conformation polymorphism (SSCP) analysis for exons 5–8 was fol