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Mutations of the Human Homolog of Drosophila patched in the Nevoid Basal Cell Carcinoma Syndrome

โœ Scribed by Heidi Hahn; Carol Wicking; Peter G Zaphiropoulos; Mae R Gailani; Susan Shanley; Abirami Chidambaram; Igor Vorechovsky; Erika Holmberg; Anne Birgitte Unden; Susan Gillies; Kylie Negus; Ian Smyth; Carolyn Pressman; David J Leffell; Bernard Gerrard; Alisa M Goldstein; Michael Dean; Rune Toftgard; Georgia Chenevix-Trench; Brandon Wainwright; Allen E Bale


Book ID
117268122
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
823 KB
Volume
85
Category
Article
ISSN
0092-8674

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Mutations in the human homologue of Dros
โœ Katsunori Fujii; Yoichi Kohno; Katsuo Sugita; Mihoko Nakamura; Yoichi Moroi; Kaz ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 331 KB ๐Ÿ‘ 1 views

Mutations in the human homologue of Drosophila patched (PTCH) have been identified in patients with nevoid basal cell carcinoma syndrome (NBCCS; also called Gorlin syndrome) as well as sporadic basal cell carcinomas and medulloblastomas. However, using PCR-SSCP analysis, mutations in PTCH have been