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Mutations of the FLT3 gene in adult acute myeloid leukemia: determination of incidence and identification of a novel mutation in a Thai population

✍ Scribed by Chirayu U. Auewarakul; Narongrit Sritana; Chanin Limwongse; Wanna Thongnoppakhun; Pa-thai Yenchitsomanus

Book ID
113512704
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
501 KB
Volume
162
Category
Article
ISSN
0165-4608

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## Abstract Mutations in the nucleophosmin (__NPM1__) gene have been recently described to occur in about one‐third of acute myeloid leukaemias (AMLs) and represent the most frequent genetic alteration currently known in this subset, specially in those with normal karyotype. This study explored the