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Mutations of RegIα are associated with enterochromaffin-like cell tumor development in patients with hypergastrinemia

✍ Scribed by Andrew D. Higham; Lisa A. Bishop; Rod Dimaline; Colin G. Blackmore; Andrew C. Dobbins; Andrea Varro; David G. Thompson; Graham J. Dockray


Book ID
118522088
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
192 KB
Volume
116
Category
Article
ISSN
0016-5085

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Association of germline or somatic TP53
✍ Waka Sugawara; Yasuhito Arai; Fumio Kasai; Yuiko Fujiwara; Masayuki Haruta; Rie 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 700 KB

## Abstract Germline __TP53__ mutations are found in Li‐Fraumeni syndrome (LFS) patients, predisposed to soft tissue sarcoma and other malignancies. The mutations and succeeding genetic events are thought to cause LFS‐associated cancer, whose genetic alterations have rarely been investigated. Here,