𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Mutations of p53 gene in human colorectal cancer: Distinct frameshifts among populations

✍ Scribed by Reiping Tang; Pei-Feng Wang; Hua-Chien Wang; Jeng-Yi Wang; Ling-Ling Hsieh


Publisher
John Wiley and Sons
Year
2001
Tongue
French
Weight
77 KB
Volume
91
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Conserved region mutations of the p53 ge
✍ Petra Jernvall; Markus MΓ€kinen; Tuomo Karttunen; Jyrki MΓ€kelΓ€; Pirkko Vihko πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 French βš– 247 KB πŸ‘ 1 views

Distal colorectal cancers, especially those in the rectum, are more aggressive and more commonly recurrent than proximal cancers. We studied the possible relationship between p53-gene mutation type and location of the tumour, since mutations in the conserved areas of the p53 gene have been suggested

Correlations between p53-protein accumul
✍ Pascal Hammel; Karen Leroy-Viard; Marie-ThΓ©rΓ¨se Chaumette; Jacqueline Villaudy; πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 French βš– 254 KB

Only half of colorectal-cancer patients elicit serum antibodies in response to intratumoral p53-gene mutations. Our study was designed to compare cellular events (p53-protein accumulation and gene mutations) with the presence of circulating anti-p53 antibodies (p53-Ab). Thirty-five colorectalcancer

p53 Website and analysis of p53 gene mut
✍ Thierry Soussi; Karim Dehouche; Christophe BΓ©roud πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 331 KB

The p53 tumor suppressor gene has proven to be one of the genes most often mutated in human cancers. It involves mainly point mutations leading to amino acid substitutions in the central region of the protein which impairs normal functions. Analysis of the mutational events that target the p53 gene

Mutational analysis of the p73 Gene in h
✍ Tomotane Shishikura; Shingo Ichimiya; Toshinori Ozaki; Yoshinori Nimura; Hajime πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 French βš– 163 KB πŸ‘ 2 views

In primary breast cancer, mutations of the p53 tumor suppressor gene lead to loss of growth-suppressive properties and poor outcome. Recently, a p53-related gene, termed p73, has been cloned and its gene product possesses a function similar to p53. p73 has been mapped at chromosome 1p36.3, a region

Molecular epidemiology of human cancer r
✍ Bennett, William P.; Hussain, S. Perwez; Vahakangas, Kirsi H.; Khan, Mohammed A. πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 340 KB πŸ‘ 1 views

The p53 tumour suppressor gene is at the crossroads of a network of cellular pathways including cell cycle checkpoints, DNA repair, chromosomal segregation, and apoptosis. These pathways have evolved to maintain the stability of the genome during cellular stress from DNA damage, hypoxia, and activat