Mutations of Fas (APO-1/CD95) and p53 Genes in Nonmelanoma Skin Cancer
β Scribed by Laura Boldrini; Barbara Loggini; Silvia Gisfredi; Ylenia Zucconi; Fulvia Baldinotti; Antonella Fogli; Paolo Simi; Gregorio Cervadoro; Paolo Barachini; Fulvio Basolo; Raffaele Pingitore; Gabriella Fontanini
- Book ID
- 106297937
- Publisher
- Springer-Verlag
- Year
- 2003
- Tongue
- English
- Weight
- 259 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1203-4754
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It is now believed that genes regulating apoptosis are also important variables in cancer development. Fas, a transmembrane protein of the tumour necrosis factor receptor family, is a key molecule for cell death signalling. The mutation of the primary structure of the Fas gene might also be one of t
FIGURE 1 -Immunoblot analyses identify 40 kDa (Fas) and 45 kDa (FasL) proteins.