𝔖 Bobbio Scriptorium
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Mutations occur in the Ig S region but rarely in S regions prior to class switch recombination

✍ Scribed by Schrader, C. E.


Book ID
111751523
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
527 KB
Volume
22
Category
Article
ISSN
0261-4189

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## Abstract Ig class switch recombination (CSR) is dependent upon the expression of activation‐induced deaminase and targeted to specific isotypes by germ‐line transcript expression and isotype‐specific factors. NF‐κB plays critical roles in multiple aspects of B cell biology and has been implicate