Mutations in TWIST, a basic helix–loop–helix transcription factor, in Saethre-Chotzen syndrome
✍ Scribed by Howard, Timothy D.; Paznekas, William A.; Green, Eric D.; Chiang, Lydia C.; Ma, Nancy; Luna, Rosa Isela Ortiz De; Delgado, Costanza Garcia; Gonzalez-Ramos, Mario; Kline, Antoine D.; Jabs, Ethylin Wang
- Book ID
- 109914977
- Publisher
- Nature Publishing Group
- Year
- 1997
- Tongue
- English
- Weight
- 844 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1061-4036
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Basic helix-loop-helix (bHLH) transcription factors have been shown to play an important role in controlling cell type determination and differentiation. TWIST, a member of the bHLH transcription factor family, is involved in the development of mesodermally derived tissue, including the skeleton. We
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