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Mutations in theWFS1gene are a frequent cause of autosomal dominant nonsyndromic low-frequency hearing loss in Japanese

โœ Scribed by Hisakuni Fukuoka; Yukihiko Kanda; Shuji Ohta; Shin-ichi Usami


Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
187 KB
Volume
52
Category
Article
ISSN
1435-232X

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Mutations in the Cx26 gene have been shown to cause autosomal recessive nonsyndromic hearing loss (ARNSHL) at the DFNB1 locus on chromosome 13q12. Using direct sequencing, we screened the Cx26 coding region of affected and nonaffected members from seven ARNSHL families either linked to the DFNB1 loc