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Mutations in the γ2 chain gene (LAMC2) of kalinin/laminin 5 in the junctional forms of epidermolysis bullosa

✍ Scribed by Pulkkinen, Leena; Christiano, Angela M.; Airenne, Tomi; Haakana, Heli; Tryggvason, Karl; Uitto, Jouni


Book ID
109915392
Publisher
Nature Publishing Group
Year
1994
Tongue
English
Weight
646 KB
Volume
6
Category
Article
ISSN
1061-4036

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Molecular basis for the dystrophic forms
✍ Jouni Uitto; Angela M. Christiano 📂 Article 📅 1994 🏛 Springer-Verlag 🌐 English ⚖ 722 KB

Significant progress has recently been made in understanding the molecular basis of heritable skin diseases, such as epidermolysis bullosa, a group of mechano-bullous genodermatoses. In particular, the dystrophic forms of epidermolysis bullosa have been shown to result from distinct mutations in the