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Mutations in the β-propeller domain of the Drosophila brain tumor (brat) protein induce neoplasm in the larval brain

✍ Scribed by Arama, Eli; Dickman, Dalia; Kimchie, Ziva; Shearn, Allen; Lev, Zeev

Book ID
110064027
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
750 KB
Volume
19
Category
Article
ISSN
0950-9232

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## Abstract Mutations in the region corresponding to the N‐terminal phosphorylation sites (codons 1–51) of the rat β‐catenin gene __(Ctnnb1)__ were investigated in rat colon tumors induced by 1‐hydroxyanthraquinone (1‐HA) plus methylazoxymethanol (MAM) acetate, by using polymerase chain reaction (P