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Mutations in the TIGR Gene in Familial Primary Open-Angle Glaucoma in Japan

โœ Scribed by Yasuyuki Suzuki; Shiroaki Shirato; Fumiko Taniguchi; Kunitoshi Ohara; Kiyomi Nishimaki; Shigeo Ohta


Book ID
117852212
Publisher
American Society of Human Genetics
Year
1997
Tongue
English
Weight
255 KB
Volume
61
Category
Article
ISSN
0002-9297

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A gene for juvenile onset, open angle glaucoma (JOAG) has been localized to chromosome 1q21-31 in several families. Mutations in the trabecular meshwork-induced glucocorticoid response protein (TIGR) gene, which maps to this region, recently have been found in families segregating both JOAG and a la