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Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation

✍ Scribed by Berkel, Simone; Marshall, Christian R; Weiss, Birgit; Howe, Jennifer; Roeth, Ralph; Moog, Ute; Endris, Volker; Roberts, Wendy; Szatmari, Peter; Pinto, Dalila


Book ID
109914611
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
461 KB
Volume
42
Category
Article
ISSN
1061-4036

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## Abstract Linkage to 7q has been the most robust genetic finding in familial autism. A previous scan of multiplex families with autism spectrum disorders found a linkage signal of genome‐wide significance at D7S530 on 7q32. We searched a candidate imprinted region at this location for genetic var