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Mutations in the PIT-1 gene in children with combined pituitary hormone deficiency

✍ Scribed by Kohji Ohta; Yoshitaka Nobukuni; Hiroshi Mitsubuchi; Shigehiro Fujimoto; Nobutake Matsuo; Hiroshi Inagaki; Fumio Endo; Ichiro Matsuda


Book ID
115765728
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
352 KB
Volume
189
Category
Article
ISSN
0006-291X

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To ascertain the molecular background of combined pituitary hormone deficiency, screening for mutations in the pituitaryspecific transcription factor (Pit-1/GHF-1) gene (PIT1) was performed on a cohort of 15 children from Russia with combined growth hormone (GH)/prolactin (Prl)/thyroidstimulating ho