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Mutations in the myosin VIIA gene cause non-syndromic recessive deafness

✍ Scribed by Liu, Xue-Zhong; Walsh, James; Mburu, Philomena; Kendrick-Jones, John; Cope, M. Jamie T.V.; Steel, Karen P.; Brown, Steve D.M.


Book ID
109916304
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
435 KB
Volume
16
Category
Article
ISSN
1061-4036

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Mutation analysis of the mouse myosin VI
✍ Philomena Mburu; Xue Zhong Liu; James Walsh; Dennis Saw; M. Cope; Fernando Gibs πŸ“‚ Article πŸ“… 1997 πŸ› Blackwell Publishing 🌐 English βš– 567 KB

The shaker‐1 (__Myo7a__) mouse deafness locus is encoded by an unconventional myosin gene: myosin VIIA [Gibson, Walsh, Mburu, Varela, Brown, Antonio, Biesel, Steel and Brown (1995) Nature (London) 374, 62–64]. The myosin VIIA gene is expressed in hair cells in the cochlea, where it is thought to fun