## Abstract Allelic imbalance (AI) on chromosome arm 22q has been detected in 20%β40% of colorectal cancers, suggesting that this chromosome arm has a tumorβsuppressor gene involved in colorectal carcinogenesis. Recently, we isolated a candidate tumorβsuppressor gene, __MYO18B__, at 22q12.1, that i
Mutations in the candidate tumour suppressor gene FLJ12973 on chromosome 15q15 are rare in colorectal cancer
β Scribed by Christina Fleischmann; Stephen Bevan; James C Neil; Anne Terry; Richard S Houlston
- Book ID
- 117467786
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 76 KB
- Volume
- 196
- Category
- Article
- ISSN
- 0304-3835
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Loss of heterozygosity (LOH) on the short arm of chromosome 8 occurs at high frequencies in many tumor types, including colorectal carcinoma. We have previously used microcellβmediated chromosome transfer (MMCT) to map an approximately 7.7 Mb colorectal cancer suppressor region (CRCSR)
## Abstract Abnormalities affecting tumour suppressor genes on chromosome 5q21 are increasingly recognised as important in the pathogenesis of a variety of human cancers, particularly of the gastrointestinal tract. We have examined a series of gastric and pancreatic cancers from European patients f