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Mutations in KIT and RAS are frequent events in pediatric core-binding factor acute myeloid leukemia

✍ Scribed by Goemans, B F; Zwaan, Ch M; Miller, M; Zimmermann, M; Harlow, A; Meshinchi, S; Loonen, A H; Hählen, K; Reinhardt, D; Creutzig, U

Book ID: 110056392
Publisher: Nature Publishing Group
Year: 2005
Tongue: English
Weight: 223 KB
Volume: 19
Category: Article
ISSN: 0887-6924
DOI: 10.1038/sj.leu.2403870

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## Abstract CCAAT/enhancer binding protein‐alpha (__CEBPA__) belongs to a family of leucine zipper transcription factors necessary for late differentiation events of many cell types. __CEBPA__ gene has recently been recognized as the target of genetic alterations in acute myeloid leukemia (AML). __